(Reuters Health) - People who suffer from posttraumatic stress disorder (PTSD) and other stress-related psychiatric issues may be more likely to develop autoimmune diseases than individuals who don’t, a Swedish study suggests. Researchers studied 106,464 people diagnosed with stress disorders. 126,652 of their siblings without stress disorders, and more than 1 million other individuals in the Swedish population who didn’t have stress disorders. They were able to track half these people for at least 10 years. During the study, individuals with PTSD were 46 percent more likely to develop an autoimmune disorder, and more than twice as likely to develop at least three autoimmune disorders, compared to adults without stress disorders. “Severe or prolonged emotional stress causes alterations in multiple bodily functions through dysregulation in the release of stress hormones,” said lead study author Dr. Huan Song of the University of Iceland in Reykjavík … [Read more...] about Stress disorders tied to increased risk of autoimmune diseases
Ulcerative colitis autoimmune disease
After disappointing sales of its weight-loss drug, Belviq, San Diego’s Arena Pharmaceuticals faced a bleak future.The company had spent far more on developing the drug, including extensive clinical trials, than it could hope to recoup. And it had no obvious replacement.That was the 2015 Arena Pharmaceuticals.Today’s Arena is a different company. It has replaced its leadership, got out of the weight-loss market and redirected efforts to other ailments, especially autoimmune diseases, in which the immune system attacks the body.Many of these diseases have no good option. While they may affect fewer patients than obesity, these are patients in dire need of better treatment.Arena shares have surged this week on promising mid-stage trial results for its drug etrasimod in ulcerative colitis. It puts patients in remission, and may also be useful in other inflammatory bowel diseases.Arena closed Friday at $41.88, up 70 cents from Thursday.The company surged Wednesday to close at at … [Read more...] about Arena Pharma recovers from weight-loss failure
Collagenous colitis refers to a type of microscopic colitis characterized by a thick band of collagen under the lining of the colon. In this article, learn about the symptoms, causes, and treatment of collagenous colitis. Collagenous colitis is a type of microscopic colitis, characterized by a thick, non-elastic band of collagen under the lining of the colon. Collagen is a type of structural protein in the body. It is described as a type of microscopic colitis because the inflammation it causes can only be seen under the microscope. Unlike most inflammatory bowel conditions, collagenous colitis is not considered a risk factor for colon cancer. The term microscopic colitis usually refers to both collagenous colitis and lymphocytic colitis. Both conditions share the same signs, symptoms, diagnostic tests, and treatment process. Some research also shows that collagenous colitis and lymphocytic colitis may, in fact, be different stages of the same condition. Collagenous colitis is … [Read more...] about What is collagenous colitis?
Credit: iStock.com/AlexLMX Hypervitaminosis B is a condition where there is too much vitamin B intake, especially in supplement form. As a result, too much vitamin B symptoms may include nerve toxicity, jaundice and liver toxicity, nausea, and digestive issues. Vitamin B complex supplements comprise a combination of all B vitamins, which include: Vitamin B1 (thiamin) Vitamin B2 (riboflavin) Vitamin B3 (niacin) Vitamin B5 (pantothenic acid) Vitamin B6 (pyridoxine) Vitamin B9 (folic acid) Vitamin B12 (cobalamin) Since B vitamins are water soluble, excess amounts will not build up in the body. Instead, they will be excreted through the urine. That being said, taking exceptionally high dosages of these B complex vitamins can lead to a variety of health risks and side effects. This article will detail the major side effects of too much vitamin B, including lung cancer in men and the effect of too much vitamin B6 while pregnant, as well as the specific health risks associated with too much … [Read more...] about Hypervitaminosis B: Side Effects of Too Much Vitamin B
Panniculitis causes large, tender bumps to form under the skin. They usually occur on the lower legs but can affect other parts of the body. In this article, learn about the causes and types of panniculitis, as well as how it is treated. Panniculitis is a relatively uncommon skin disorder. It causes large bumps to appear under the skin, usually on the lower legs. The bumps, also called nodules, are tender to touch and may look red or purple. Nodules are caused by an inflammation in the layer of fat under the skin. This layer is called the panniculus adiposus and is used for keeping the body warm. Many types of panniculitis exist, including those caused by infections, cold temperatures, and side effects of medication. The most common type is erythema nodosum where nodules are found on the shins. This type is most often seen in women and young adults. The main symptoms of panniculitis include: Large bumps that are tender to touch. The lumps, which may appear red or purple, are located … [Read more...] about What is panniculitis? Causes and treatment