Home Pregnancy parenting Baby Baby on June 13, 2022 Alexander disease is a rare neurodegenerative disease; it falls into the category of leukodystrophies, a group of rare and inherited neurological disorders that result from problems in myelin, or the brain's "white matter". However, the condition is more of a disease of astrocytes (an astrogliopathy) than a white matter disease (leukodystrophy). It is named after the physician W. Stewart Alexander who first described the condition in 1949. In Alexander disease, the destruction of white matter is accompanied by the formation of Rosenthal fibres, unusual lumps of protein that accumulate in astrocytes, or non-nerve cells of the brain, leading to improper functioning of the nervous system. [1] The condition is commonly found in infants as the symptoms start to show during the first two years of life. However, the symptoms can begin at any stage of life. The condition, … [Read more...] about Alexander Disease In Infants: Causes, Symptoms, Diagnosis And Treatments