(Reuters) - Aquinox Pharmaceuticals Inc said on Wednesday it planned to stop developing its main drug to treat bladder pain syndrome as it failed to meet the main goal of a late-stage trial, pushing its shares down as much as 85 percent. “We will be undertaking a thorough evaluation of our pipeline and other strategic options available to the company,” Chief Executive Officer David Main said in a statement. The treatment, rosiptor, failed to show statistically significant reduction in bladder pain, the company said. Bladder pain syndrome, or interstitial cystitis, is a chronic condition characterized by bladder pressure, bladder pain and pelvic pain. About 5.5 million adults in the United States suffer from symptoms consistent with bladder pain syndrome, the company said. The company had about $93 million in cash on hand at the end of its first quarter. Last month, Aquinox announced a licensing agreement with Astellas Pharma that gave the Tokyo-based drugmaker the … [Read more...] about Aquinox to stop development of lead drug; shares plunge
Janssen research development
Monday, June 11, 2018 by: Edsel Cook Tags: Anesthetic, antidepressant drugs, Antidepressants, badmedicine, Big Pharma, depression, drug abuse, electroconvulsive therapy, esketamine, hallucinogen, hallucinogenic drug, ketamine, party drug, Prescription drugs, severe depression, treatments (Natural News) Ketamine started out as an anesthetic for surgeries, only to quickly get abused as a hallucinogenic party drug. Now a U.S. study is claiming it can serve as a “fast-acting” treatment for people afflicted with clinical depression, an article from the BBC reported. The researchers administered ketamine to participants via nasal spray. It claimed that volunteers with symptoms of depression showed “significant” improvements within 24 hours of treatment. The U.K.’s Royal College of Psychiatrists (RCP) described the study’s findings as a big step for ketamine, which has not yet been accepted as an antidepressant by the … [Read more...] about Ketamine seen as “fast-acting” for those who suffer from depression
But before leaving a comment, please review these notes about our policy. You are responsible for any comments you leave on this site. This site is primarily a forum for discussion about the quality (or lack thereof) in journalism or other media messages (advertising, marketing, public relations, medical journals, etc.) It is not intended to be a forum for definitive discussions about medicine or science. We will delete comments that include personal attacks, unfounded allegations, unverified claims, product pitches, profanity or any from anyone who does not list a full name and a functioning email address. We will also end any thread of repetitive comments. We don”t give medical advice so we won”t respond to questions asking for it. We don”t have sufficient staffing to contact each commenter who left such a message. If you have a question about why your comment was edited or removed, you can email us at … [Read more...] about Janssen’s claim that Xarelto benefits frail patients better than warfarin built on frail research
KETAMINE could help ease depression and suicidal thoughts in a matter of hours, experts have found. In as little as four hours, the drug showed signs of working, new research shows. People were given specific molecules from the party drug, Special K, in nasal spray form. They also took their regular antidepressant medication. Scientists in the US then compared the effects to a group of people taking just their standard treatment for depression. They looked at the effects of treatment at four hours, 24 hours and 25 days. The results showed "significant improvement" in depression scores and fewer people reporting suicidal thoughts when they took ketamine alongside their antidepressants. That improvement was only seen at four hours and 24 hours, though. At 25 days, the ketamine showed no extra benefit to the antidepressants, researchers found. In determining suicide risk, the team used both the patient's feelings and their doctor's opinion together. KETAMINE: THE RISKSKETAMINE can … [Read more...] about Party drug ketamine can ‘help beat depression and suicidal thoughts in FOUR HOURS’
Published 5:15 pm, Wednesday, March 28, 2018 Image 1of/1 CaptionClose Image 1 of 1 How does diabetes affect kidney health? 1 / 1 Back to Gallery (BPT) - The kidneys play an important role in maintaining our overall health. While these bean-shaped organs perform multiple functions, a primary role is filtration, critical to clearing waste such as urea and to keeping the body’s fluids and electrolytes in balance. Good kidney health is essential for everyone, yet today, more than 30 million adults in the U.S. have chronic kidney disease (CKD), and there has been little new innovation to treat kidney disease in over a decade. So how does diabetes, an all-too-common cardiovascular and metabolic (CVM) condition, impact our kidneys? The most common causes of CKD are diabetes and high blood pressure. For those with diabetes, the body does not make enough insulin or use normal amounts of insulin properly. Because of the high levels … [Read more...] about How does diabetes affect kidney health?