FENTANYL is a prescription painkiller that gives relief from chronic diseases and is said to be 100 times more powerful than morphine. Here's all you need to know about the drug that Prince accidentally overdosed on - and has been linked to an increasing amount of deaths in the UK. What is Fentanyl? Fentanyl is a strong opioid painkiller that is used by many patients around the world suffering from chronic conditions. It works by stopping pain signals being sent to the nerves in the brain, meaning users do not suffer any discomfort. Due to its strength, it is highly controlled by doctors and pharmacists and cannot be prescribed for children. It can be administered in patch form or can be injected into the body via a needle or a drip. Hampshire Police Detective Superintendent Paul Barton, head of organised and serious crime in Southampton, said a major operation revealed the drug is becoming alarmingly more common. He said: "It's a cutting agent that is mixed with various drugs, … [Read more...] about What is Fentanyl, what is the drug used for, are there side effects and how was it linked to Prince’s death?
(Reuters) - The U.S. Food and Drug Administration declined to approve Pain Therapeutics Inc’s abuse-deterrent opioid treatment Remoxy for the fourth time, sending the company’s shares down 35 percent to a record low. Remoxy is a capsule formulation of the commonly used opioid oxycodone, and the high-viscosity drug mass helped prevent abuse, according to the company. However, in a letter to the company the agency said the data failed to show that benefits outweighed the associated risks. Pain Therapeutics, valued at about $17 million, said it would now initiate a strategic reorganization to focus on its Alzheimer’s disease treatments and diagnostic products. PTI-125, the company’s lead drug candidate in the Alzheimer’s pipeline, showed positive data in its early-stage study conducted in October. “They are kind of backed into a corner when their drug gets rejected and there does not seem to be a path forward,” said Kevin Kedra, an analyst at … [Read more...] about FDA declines to approve Pain Therapeutics’ opioid drug, shares plunge
A HUNGRY Indiana child died after eating 180 times the lethal amount of methamphetamine — which he thought was a breakfast cereal, according to reports. Eight-year-old Curtis Collman III woke up early on June 21 and told his dad, Curtis Gilbert Collman II, that he wanted something to eat, the man told authorities, WDRB reported. Collman II, 41 said there was no food in the Seymour house. But there was meth, that he left on a clear glass plate, he told authorities. Meth can be crystal like, or brownish in colour and could have been mistaken for cereal in low light, the outlet noted. The child ate a staggering amount of the drug — 18,000 nanograms — toxicology results released this week revealed, the Seymour Tribune reported. Collman II, 41, noticed his son was feeling sick around 10 a.m. and asked a friend to come over to help check him out, according to police documents obtained by NBC-Wave3. But instead of taking the boy to a hospital like his friend suggested, … [Read more...] about Boy, 8, dies after ‘mistaking his dad’s drug stash for breakfast cereal and downing spoonfuls of meth’
Pain Therapeutics said on Monday that the U.S. Food and Drug Administration declined to approve its opioid drug for the management of severe pain as the benefits of the drug did not outweigh the risk. "This is a bizarre conclusion to reach, especially during a time of staggering human and economic toll created by opioid abuse and addiction," said Chief Executive Officer Remi Barbier said in a statement. The FDA's "complete response letter" marks the latest setback to the U.S. drug developer and the treatment, Remoxy ER, which has failed to get marketing approval on the past three attempts. The drug developer also said it had initiated a strategic reorganization to align its resources to focus on its treatments and diagnostic products for Alzheimer's disease. The drug is a capsule formulation of the commonly-used opioid oxycodone The regulator's decision comes amid increased public and regulatory scrutiny in the United States over the use of opioid drugs, the abuse of which has reached … [Read more...] about FDA Declines to Approve Pain Therapeutics’ Abuse-Deterrent Opioid Drug
By Washington Post | PUBLISHED: August 6, 2018 at 4:26 am | UPDATED: August 6, 2018 at 4:34 am By Samantha Schmidt | The Washington Post In Demi Lovato’s first public statement since being hospitalized for an apparent drug overdose, the pop star says she is focused on her sobriety and “road to recovery.” “I have always been transparent about my journey with addiction,” Lovato wrote in a letter posted on her Instagram. “What I’ve learned is that this illness is not something that disappears or fades with time. It is something I must continue to overcome and have not done yet.” The singer thanked God “for keeping me alive and well,” as well as her fans, whose “positive thoughts and prayers have helped me navigate through this difficult time.” She also thanked her family and the staff at Cedars-Sinai Medical Center in Los Angeles. “Without them I wouldn’t be here writing this letter to all of … [Read more...] about Demi Lovato breaks silence after apparent drug overdose: ‘I will keep fighting’